Leptospirosis is a type of bacterial infection spread by animals. It is caused by a strain of bacteria called leptospira.
In 90% of cases, leptospirosis only causes mild flu-like symptoms, such as headache, chills and muscle pain.
However, in some cases the infection is more severe and can cause life-threatening problems, including organ failure and internal bleeding. In its most severe form, leptospirosis is also known as Weil's disease.
The common mild symptoms mean that most leptospirosis infections are hard to diagnose. Diagnosis is easier if the infection causes more serious problems.
A detailed history of places you have been and any animals you have been in contact with can help with a diagnosis.
Leptospirosis is spread to humans by animals.
You can catch leptospirosis by touching soil or water contaminated with the urine of wild animals infected with the leptospira bacteria.
Animals known to be carriers of the leptospira bacteria include cattle, pigs, dogs and rodents, particularly rats.
Although the condition is uncommon in the UK, people who regularly deal with animals, such as farmers and vets, have a higher risk of developing leptospirosis.
You may also be at a higher risk if you frequently come into contact with sources of freshwater, such as rivers and lakes. This might be because of your occupation or through taking part in recreational activities such as water sports and fishing.
Transmission between humans is incredibly rare.
Read more about the causes of leptospirosis.
The risk of contracting leptospirosis in the UK is so low that you don't need to take drastic measures to avoid the condition.
If you work with animals – dead or alive – or are in regular contact with freshwater sources, you can help protect yourself from leptospirosis by wearing appropriate protective clothing and by cleaning and dressing wounds.
This advice is particularly useful if you are travelling to an area where leptospirosis is more common.
Read more about preventing leptospirosis.
Leptospirosis is treated with a course of antibiotics.
For mild forms of leptospirosis, antibiotic tablets that can be taken at home are usually used for about a week.
Most people with more severe leptospirosis will require admission to hospital so the functions of their body can be supported while the underlying infection is treated with injections of antibiotics.
Read more about treating leptospirosis.
The symptoms of leptospirosis usually develop abruptly seven to 14 days after exposure to the leptospira bacteria.
However, it is possible for symptoms to develop from between two and 30 days after exposure.
About 90% of leptospirosis infections only cause mild symptoms, including:
These symptoms usually resolve within five to seven days. However, in about 10% of cases people go on to experience more serious symptoms.
Severe leptospirosis infections are sometimes called Weil's disease. The symptoms of a severe infection usually develop one to three days after the more mild symptoms have passed.
The pattern of symptoms usually falls into one of three groups, depending on which organs have become infected:
In rare cases, it is possible to experience all three groups of symptoms at the same time.
If these organs are affected, you will probably experience the following symptoms:
If left untreated, your liver or kidneys may lose their ability to function. Loss of kidney function is known as kidney failure and can be fatal.
There are two ways that the brain can be affected:
Both types of brain infection cause similar symptoms, including:
If left untreated, the infection may cause brain damage and can be fatal.
A leptospirosis infection that spreads to the lungs presents the most serious health threat because it carries a significant risk of death. This is because the bacteria damage the lung tissues, which can result in massive internal bleeding and loss of lung function.
Leptospirosis is caused by a strain of bacteria called leptospira, which is found in certain animals and can spread to humans.
These animals include:
It is rare to catch leptospirosis from domestic pets, although there have been cases where the infection was caught from pet rats.
An animal carrying the leptospira bacteria may show no outward signs of illness. The bacteria live inside the animal's kidneys and can be passed out in their urine. Bacteria passed into soil or water can survive for several weeks or even months.
It is possible to become infected with the leptospira bacteria if contaminated water or soil comes into contact with your eyes, mouth, nose or any open cuts in the skin. The bacteria can also be spread through rodent bites or by drinking contaminated water. Less commonly, the infection can be passed to humans who come into close physical contact with the blood or tissues of an infected animal.
Outbreaks of leptospirosis can also occur, particularly at events that involve close contact with infected fresh water sources, such as some water sports. It is also possible for people to become infected after a natural disaster, such as a flood.
Human to human transmission of infection is extremely rare, but it is thought that it may be possible during sex or by an infected mother passing it on to her baby while breastfeeding.
Leptospirosis is found throughout the world, including western Europe, but is most common in tropical and subtropical areas. This is because the leptospira bacteria are able to survive longest in hot and humid conditions.
The countries and regions where leptospirosis is most common include:
If you are travelling to these parts of the world, certain outdoor activities could bring you into contact with contaminated water or soil and may place you at a slightly higher risk of contracting leptospirosis. For example:
Areas of the developing world where there has been sudden flooding tend to have an associated outbreak of leptospirosis. This is because previously clean sources of drinking water can become contaminated by flood water.
There are several occupations that increase your risk of contracting leptospirosis. However, this risk is most significant if you are working in the parts of the world listed above, rather than in the UK. These occupations include:
Read about preventing leptospirosis for information and advice about how to reduce your risk of contracting the disease.
Leptospirosis can be difficult to diagnose in its mild early stages, as it shares symptoms with other more common infections.
Many cases may initially be mistaken for conditions such as influenza (flu). Leptospirosis is therefore usually only diagnosed if symptoms are severe.
To diagnose leptospirosis successfully, a detailed personal history is usually required. You should tell your doctor if you:
A diagnosis of leptospirosis can be confirmed by running a series of blood and urine tests to detect the presence of the leptospira bacteria in your blood or urine.
Scans such as a chest X-ray may also be carried out if it is felt your organs have been affected.
Leptospirosis is usually treated with a course of antibiotics, although their effectiveness has not been conclusively proven.
Most cases of leptospirosis are mild and can be successfully treated with a five to seven-day course of antibiotic tablets. Penicillin or a tetracycline antibiotic called doxycycline are the preferred choices.
Common side effects of antibiotics include:
These side effects should pass once you complete the course of antibiotics. An alternative antibiotic, such as erythromycin, can also be used.
It is very important that you finish the prescribed course of antibiotics, even if you are feeling better. This is because stopping treatment before all of the bacteria have been killed may trigger the return of a more serious infection.
Contact your doctor for advice if, despite treatment, your symptoms fail to improve after seven days.
More information about the medicines that are used to treat leptospirosis can be found on the [leptospirosis medicines guide page].
If you develop a more severe leptospirosis infection, you will need to be admitted to hospital. The underlying infection will be treated with intravenous antibiotics (antibiotics that are injected directly into the bloodstream).
If you have experienced organ damage, additional equipment may be required to support the functions of your body. For example:
The amount of time that you will need to spend in hospital will depend on how well you respond to the antibiotics and the extent of any organ damage. Some people may be well enough to leave hospital within a few weeks, while others may require several months of hospital care.
Although leptospirosis is rare, there are some simple steps can help reduce your chances of developing the condition.
Although rates of leptospirosis can be very low so there is no reason why you should not participate in freshwater recreational activities such as swimming, sailing, water skiing or windsurfing.
However, if you are regularly involved in freshwater activities, it is a sensible precaution to cover any cuts and grazes you have with a waterproof dressing because there are other waterborne infections that you can catch, such as hepatitis A (a viral infection) or giardiasis (an infection caused by parasites). You should also shower or bathe after freshwater activities.
If you have an occupation where you come into contact with animals (particularly rodents) or sources of contaminated water, such as farming or working with sewers or drains, wear adequate protective clothing. This could include waterproof gloves and boots, goggles and a mask.
If you are travelling to parts of the world where leptospirosis is widespread, you may wish to limit your exposure to freshwater sources, such as rivers, ponds or lakes. If you are unable to avoid these, you should ensure you wear adequate protective clothing.
You should also only drink sealed bottled water or fresh water that has been boiled. Always cover any cuts or grazes with waterproof dressings and clean any wounds as soon as possible.
Try to minimise your exposure to animal urine by avoiding areas where animals may have urinated, such as bedding and litter trays. If you suspect you have been exposed to animal urine, clean the affected area of skin as soon as possible.
Never touch a dead animal with your bare hands.
Read about the causes of leptospirosis for information on areas of the world where leptospirosis is more common.
Antibiotics can sometimes be taken as a precaution against becoming infected. However, there is limited evidence this works for leptospirosis, so the treatment is usually only used in exceptional circumstances, such as:
At the moment, there isn't a vaccine that protects humans from leptospirosis, but it is possible to vaccinate cattle, dogs and some other animals.
If you think you may be at risk of contracting leptospirosis from one of your animals, you may want to consider getting them vaccinated.
Important: Our website provides useful information but is not a substitute for medical advice. You should always seek the advice of your doctor when making decisions about your health.